A user over on Reddit has what is a very ambitious theory when it comes to the next Mass Effect game. Of course you cannot expect Bioware to take this into account, but it does seem to be quite plausible when you take into account the comments.
The theory can be found below.
During the Reaper war, an influential and massively rich business owner (not necessarily sure who) decided that they needed a an escape from the impending death of all organic life. So they gather together as many scientists as they can and set them to work modifying a mass relay. The goal is to find a way to change its destination; specifically, force it to send ships to the Andromeda galaxy.
The head of this project gathers their closest friends and family, plus mercenaries for protection and tonnes of raw materials for trading purposes, and sets of in secret (not wanting the Reapers to follow, who knows how thorough those things are). Mass Effect 4 would tell the story of this group’s arrival in Andromeda, and the player character would be one of the mercenaries and preferably have full control over race, gender, class etc. I know it’s unlikely that this is what BioWare has planned, but I wanted to share the idea because I think it could really be fantastic for a number of reasons.
I’ve been thinking about this stuff a lot lately, let’s hope we finally get a look at ME4 next month at E3.