Recently Rockstar along with Take Two interactive filed a trademark for Hangar 13 and this suggests that Rockstar could be working on a new game. So it seems that while Rockstar may well be working on GTA 6, we could see Hangar 13 come out first.
There has been some talk of Hangar 13 being a DLC for GTA 5 that could be a follow up to the UFO secrets that are hidden in GTA 5.
We have also heard that Hangar 13 may be a rebranding of Agent, this was a game that was first announced in 2009 and then it faded away, however the Agent trademark was renewed just last year.
Of course as Rockstar have only just filed the petition for Hangar 13 we are not likely to hear anything about for some time to come.